SERUM 25-OH VITAMIN D IN CHILDREN WITH BRONCHIAL ASTHMA

Abstract

Vitamin D comprises a group of fat-soluble sterol compounds that can be ingested orally or synthesized
endogenously in the skin after exposure to Ultraviolet (UV) B light. Several hypotheses have been proposed that
vitamin D plays role in development of allergy and asthma. We determined 25-OH vitamin D in 36 cases of bronchial
asthma versus 16 controls. Vitamin D level in asthmatic cases ranged from 88.64-252.6 nmol/l , while in control from
80-99nmol/l . Both levels still in normal range (80-250nml/l) according to current literatures. When we make
stratification of vitamin D level in both cases and controls ,we found only 2 cases 5.6 % have level in range of
control 80-100 nmol/l “ control ranges , Remaining patient 94.4 % remained above control range ,. Also, we found
significant statistical higher vitamin D level in asthmatic cases in relation to control (178.03±36..44 versus,
88.52±4.91nmol/l P was 0.000) , No significant difference in vitamin D in asthmatic cases in relation to age ,sex
,weight or respiratory distress .Also , no relation found to laboratory parameters including Hb level ,Htc. value
.,,WBCs and ESR . These results highlight the necessity to updates and revise the reference range of vitamin D
in relation to respiratory and immunological function . Also highlight importance of revision of multivitamin and
vitamin D supplements for infants