EFFECT OF LAPAROSCOPIC OVARIAN CYSTECTOMY FOR ENDOMETRIOMA ON OVARIAN RESERVE

Abstract

ABSTRACT Background: To assess the effect of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve by markers as Anti-Mullerian Hormone and Follicle Stimulating Hormone. Subjects: 48 Women of reproductive age who had ultrasonographic diagnosis of endometrioma measuring>3cm whether unilateral or bilateral and subjected to laparoscopic excision. Methods: From January 2017 to December 2017, Women with endometrioma underwent to laparoscopic excision. Serum AMH and FSH were determined preoperatively and 3months postoperative. Results: There was a statistically significant reduction in postoperative mean value of AMH ( 2.04+ 1.69 ) when compared to the preoperative mean value of AMH (2.59+ 1.85 ) and a statistically significant rise in postoperative mean value of serum FSH (7.23+ 1.48 ), when compared to preoperative mean value of FSH (5.50+ 1.85 ). Post-operative AMH decreases were greater in patients with endometriomas > 5cm in diameter compared with smaller ones and in patients with bilateral endometriomas compared with unilateral ones. Conclusion: Laparoscopic cystectomy for endometrioma has an adverse impact on ovarian reserve. Bilaterality and size of endometrioma increase the adverse effect of Laparocopic ovarian cystectomy on the ovarian reserve. Keywords: Endometrioma, Laparoscopic cystectomy, Anti-Mullerian hormone, Follicle stimulating hormone.